HLA class I and class II polymorphism in a population from south‐eastern Tunisia (Gabes Area)
Identifieur interne : 000451 ( Main/Exploration ); précédent : 000450; suivant : 000452HLA class I and class II polymorphism in a population from south‐eastern Tunisia (Gabes Area)
Auteurs : A. Hajjej [Tunisie] ; G. Hajjej [Tunisie] ; W. Y. Almawi [Bahreïn] ; H. Kaabi [Tunisie] ; A. El-Gaaied [Tunisie] ; S. Hmida [Tunisie]Source :
- International Journal of Immunogenetics [ 1744-3121 ] ; 2011-06.
Abstract
The gene frequencies of HLA class I and class II alleles were investigated in 95 healthy Tunisian individuals from Gabes. Our aim was to compare the genetic relationship between Gabesians and Mediterraneans and sub‐Sahara Africans using genetic distances, Neighbour‐Joining dendrograms, correspondence and haplotypes analysis, thereby providing additional information about evolutionary history of modern‐day Tunisians. Subjects were unrelated and of both genders, and HLA class I and class II genes were genotyped using the polymerase chain reaction‐sequence specific primer (PCR‐SSO) technique. Our data show that south‐eastern Tunisians (Gabes area) are related to present‐day North Africans (Algerians, Moroccans, Tunisians) and Iberians (Spaniards, Basques), and along with other North Africans, appear to be genetically related to Berbers, an indication that the Arab invasion (7th–11th centuries) of North Africa had minimal contribution on the HLA makeup of North Africans. On the other hand, Iberians including Spaniards and Basques show relatedness to (native Tunisian) Berbers, suggesting that the gene flow of 7th century AD invaders was also low in Iberians. In conclusion, the successive invasions of North Africa in general, and Tunisia in particular, did not modify markedly the genetic makeup of present‐day Tunisians. With the exception of Greeks who have a sub‐Saharan genetic profile, all Mediterranean populations depict a typical mediterranean substratum.
Url:
DOI: 10.1111/j.1744-313X.2011.01003.x
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000286
- to stream Istex, to step Curation: 000150
- to stream Istex, to step Checkpoint: 000301
- to stream Main, to step Merge: 000452
- to stream Main, to step Curation: 000451
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">HLA class I and class II polymorphism in a population from south‐eastern Tunisia (Gabes Area)</title><author><name sortKey="Hajjej, A" sort="Hajjej, A" uniqKey="Hajjej A" first="A." last="Hajjej">A. Hajjej</name></author><author><name sortKey="Hajjej, G" sort="Hajjej, G" uniqKey="Hajjej G" first="G." last="Hajjej">G. Hajjej</name></author><author><name sortKey="Almawi, W Y" sort="Almawi, W Y" uniqKey="Almawi W" first="W. Y." last="Almawi">W. Y. Almawi</name></author><author><name sortKey="Kaabi, H" sort="Kaabi, H" uniqKey="Kaabi H" first="H." last="Kaabi">H. Kaabi</name></author><author><name sortKey="El Aaied, A" sort="El Aaied, A" uniqKey="El Aaied A" first="A." last="El-Gaaied">A. El-Gaaied</name></author><author><name sortKey="Hmida, S" sort="Hmida, S" uniqKey="Hmida S" first="S." last="Hmida">S. Hmida</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:A9707B6805E406C0231177B30C7ACF722FE0C9F0</idno><date when="2011" year="2011">2011</date><idno type="doi">10.1111/j.1744-313X.2011.01003.x</idno><idno type="url">https://api.istex.fr/document/A9707B6805E406C0231177B30C7ACF722FE0C9F0/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000286</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000286</idno><idno type="wicri:Area/Istex/Curation">000150</idno><idno type="wicri:Area/Istex/Checkpoint">000301</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000301</idno><idno type="wicri:doubleKey">1744-3121:2011:Hajjej A:hla:class:i</idno><idno type="wicri:Area/Main/Merge">000452</idno><idno type="wicri:Area/Main/Curation">000451</idno><idno type="wicri:Area/Main/Exploration">000451</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">HLA class I and class II polymorphism in a population from south‐eastern Tunisia (Gabes Area)</title><author><name sortKey="Hajjej, A" sort="Hajjej, A" uniqKey="Hajjej A" first="A." last="Hajjej">A. Hajjej</name><affiliation wicri:level="3"><country xml:lang="fr">Tunisie</country><wicri:regionArea>National Blood Transfusion Center, Tunis</wicri:regionArea><placeName><settlement type="city">Tunis</settlement><region nuts="2">Gouvernorat de Tunis</region></placeName></affiliation></author><author><name sortKey="Hajjej, G" sort="Hajjej, G" uniqKey="Hajjej G" first="G." last="Hajjej">G. Hajjej</name><affiliation wicri:level="1"><country xml:lang="fr">Tunisie</country><wicri:regionArea>Faculty of Sciences of Sfax</wicri:regionArea></affiliation></author><author><name sortKey="Almawi, W Y" sort="Almawi, W Y" uniqKey="Almawi W" first="W. Y." last="Almawi">W. Y. Almawi</name><affiliation wicri:level="1"><country xml:lang="fr">Bahreïn</country><wicri:regionArea>College of Medicine and Medical Sciences, Arabian Gulf University, Manama</wicri:regionArea><wicri:noRegion>Manama</wicri:noRegion></affiliation></author><author><name sortKey="Kaabi, H" sort="Kaabi, H" uniqKey="Kaabi H" first="H." last="Kaabi">H. Kaabi</name><affiliation wicri:level="3"><country xml:lang="fr">Tunisie</country><wicri:regionArea>National Blood Transfusion Center, Tunis</wicri:regionArea><placeName><settlement type="city">Tunis</settlement><region nuts="2">Gouvernorat de Tunis</region></placeName></affiliation></author><author><name sortKey="El Aaied, A" sort="El Aaied, A" uniqKey="El Aaied A" first="A." last="El-Gaaied">A. El-Gaaied</name><affiliation wicri:level="3"><country xml:lang="fr">Tunisie</country><wicri:regionArea>Laboratory of Immunogenetics, Department of Biology, University of Tunis – El‐Manar, Tunis</wicri:regionArea><placeName><settlement type="city">Tunis</settlement><region nuts="2">Gouvernorat de Tunis</region></placeName></affiliation></author><author><name sortKey="Hmida, S" sort="Hmida, S" uniqKey="Hmida S" first="S." last="Hmida">S. Hmida</name><affiliation wicri:level="3"><country xml:lang="fr">Tunisie</country><wicri:regionArea>National Blood Transfusion Center, Tunis</wicri:regionArea><placeName><settlement type="city">Tunis</settlement><region nuts="2">Gouvernorat de Tunis</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">International Journal of Immunogenetics</title><idno type="ISSN">1744-3121</idno><idno type="eISSN">1744-313X</idno><imprint><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2011-06">2011-06</date><biblScope unit="volume">38</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="191">191</biblScope><biblScope unit="page" to="199">199</biblScope></imprint><idno type="ISSN">1744-3121</idno></series><idno type="istex">A9707B6805E406C0231177B30C7ACF722FE0C9F0</idno><idno type="DOI">10.1111/j.1744-313X.2011.01003.x</idno><idno type="ArticleID">IJI1003</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1744-3121</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The gene frequencies of HLA class I and class II alleles were investigated in 95 healthy Tunisian individuals from Gabes. Our aim was to compare the genetic relationship between Gabesians and Mediterraneans and sub‐Sahara Africans using genetic distances, Neighbour‐Joining dendrograms, correspondence and haplotypes analysis, thereby providing additional information about evolutionary history of modern‐day Tunisians. Subjects were unrelated and of both genders, and HLA class I and class II genes were genotyped using the polymerase chain reaction‐sequence specific primer (PCR‐SSO) technique. Our data show that south‐eastern Tunisians (Gabes area) are related to present‐day North Africans (Algerians, Moroccans, Tunisians) and Iberians (Spaniards, Basques), and along with other North Africans, appear to be genetically related to Berbers, an indication that the Arab invasion (7th–11th centuries) of North Africa had minimal contribution on the HLA makeup of North Africans. On the other hand, Iberians including Spaniards and Basques show relatedness to (native Tunisian) Berbers, suggesting that the gene flow of 7th century AD invaders was also low in Iberians. In conclusion, the successive invasions of North Africa in general, and Tunisia in particular, did not modify markedly the genetic makeup of present‐day Tunisians. With the exception of Greeks who have a sub‐Saharan genetic profile, all Mediterranean populations depict a typical mediterranean substratum.</div></front></TEI><affiliations><list><country><li>Bahreïn</li><li>Tunisie</li></country><region><li>Gouvernorat de Tunis</li></region><settlement><li>Tunis</li></settlement></list><tree><country name="Tunisie"><region name="Gouvernorat de Tunis"><name sortKey="Hajjej, A" sort="Hajjej, A" uniqKey="Hajjej A" first="A." last="Hajjej">A. Hajjej</name></region><name sortKey="El Aaied, A" sort="El Aaied, A" uniqKey="El Aaied A" first="A." last="El-Gaaied">A. El-Gaaied</name><name sortKey="Hajjej, G" sort="Hajjej, G" uniqKey="Hajjej G" first="G." last="Hajjej">G. Hajjej</name><name sortKey="Hmida, S" sort="Hmida, S" uniqKey="Hmida S" first="S." last="Hmida">S. Hmida</name><name sortKey="Kaabi, H" sort="Kaabi, H" uniqKey="Kaabi H" first="H." last="Kaabi">H. Kaabi</name></country><country name="Bahreïn"><noRegion><name sortKey="Almawi, W Y" sort="Almawi, W Y" uniqKey="Almawi W" first="W. Y." last="Almawi">W. Y. Almawi</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Linguistique/explor/TamazightV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000451 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000451 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Linguistique
|area= TamazightV2
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:A9707B6805E406C0231177B30C7ACF722FE0C9F0
|texte= HLA class I and class II polymorphism in a population from south‐eastern Tunisia (Gabes Area)
}}
| This area was generated with Dilib version V0.6.33. |  |